troap rabbit mab (Proteintech)
Structured Review

Troap Rabbit Mab, supplied by Proteintech, used in various techniques. Bioz Stars score: 93/100, based on 9 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/troap+rabbit+mab/pmc08339535-64-9-12?v=Proteintech
Average 93 stars, based on 9 article reviews
Images
1) Product Images from "TROAP regulates cell cycle and promotes tumor progression through Wnt/β‐Catenin signaling pathway in glioma cells"
Article Title: TROAP regulates cell cycle and promotes tumor progression through Wnt/β‐Catenin signaling pathway in glioma cells
Journal: CNS Neuroscience & Therapeutics
doi: 10.1111/cns.13688
Figure Legend Snippet: GSEA enrichment analysis of TROAP using the GEO database. (A, B) KEGG pathways were screened with the Fold change value greater than 0 and p < 0.05 as screening conditions. The dotplot showed the 19 upregulated (NES > 0) and 4 downregulated (NES < 0) pathways. (C) GSEA enrichment plots represented that enrichment of Wnt/β‐Catenin pathway. (D, E) Immunofluorescence showing overexpression of TROAP increased level of Axin2 protein in the cytoplasm of TJ905 cells compared to control, meanwhile, TROAP overexpression also upregulated the accumulation of β‐Catenin in the cytoplasm and nucleus of TJ905 cells compared to control. Immunofluorescence quantification analysis was shown in E. (F, G) Immunofluorescence assay on U251 cells transfected with TROAP siRNA (* p < 0.05, ** p < 0.01, *** p < 0.001, respectively)
Techniques Used: Immunofluorescence, Over Expression, Control, Transfection
Figure Legend Snippet: TROAP‐induced malignant phenotype via activating the Wnt/β‐Catenin signaling in glioma cells. (A, B) Western blot analysis showing the expression of Wnt/β‐Catenin signaling‐related proteins after silencing Axin2 or β‐Catenin in TJ905 cells ectopically overexpressing TROAP. The statistics were shown in the histogram C and D. The effect of TROAP overexpression on cell proliferation(E‐H), migration and invasion (I, J) was partly eliminated by silencing Axin2 or β‐Catenin (* p < 0.05, ** p < 0.01, *** p < 0.001, respectively)
Techniques Used: Western Blot, Expressing, Over Expression, Migration